Free webinar: In vitro skin sensitization potency assessment
Using GARD® to derive PoDs and safe dose levels for skin sensitizers
Chemicals | Natural Extracts | Complex Mixtures
Join our upcoming webinar to explore how GARD® enables the derivation of Points of Departure (PoDs) for Quantitative Risk Assessment (QRA) and helps establish safe dose levels for identified sensitizers.
With broad applicability to complex mixtures and new raw materials with challenging properties, GARD® offers a powerful non-animal solution in skin sensitization potency assessment.
Typical challenges you may face:
- You have a new ingredient that is a sensitizer. At what dose level is it safe to use?
- You are planning for confirmatory human patch testing (HRIPT). How can you obtain a NESIL value?
- You are performing a Risk Assessment for a new active ingredient in a complex formulation. How can you get a PoD/NESIL for QRA?
As practical examples, we will showcase scientific collaborations with Unilever, BIC, Takasago, dōTERRA, International Flavors & Fragrances (IFF) and the Research Institute for Fragrance Materials (RIFM).
Key topics
- Introduction to New Approach Methodologies (NAMs) for skin sensitization potency assessment.
- How to overcome common challenges in deriving PoDs and establishing safe dose levels for skin sensitizers.
- Case studies on Fragrances, Essential Oils, Botanical Extracts, and Complex Mixtures.
The webinar will last around 30 minutes, followed by a live Q&A. If you cannot attend the live event, make sure to register to get access to the recording.
Speaker
Andy Forreryd, PhD, Scientific Liaison Manager @ SenzaGen
- Co-developer of the GARD®skin assay (OECD TG 442E).
- Member of the ISO/TC 194/WG 8 on irritation and sensitization.
- Member of OECD expert group on respiratory sensitization.