In Vitro Laboratory Technician
About Asgard Therapeutics
Asgard Therapeutics is a privately held biotech company pioneering in vivo direct cell reprogramming for cancer immunotherapy, backed by Johnson & Johnson Innovation – JJDC, Inc., RV Invest, Novo Holdings, Boehringer Ingelheim Venture Fund, and Industrifonden. Our lead candidate, AT-108, is a first-in-class gene therapy that reprograms tumor cells into antigen-presenting dendritic cells (cDC1), triggering a personalized and potent anti-tumor immune response.
Position Overview
Asgard Therapeutics offers a creative and team-oriented work environment. The role will involve executing immune-oncology and cell reprogramming experiments in vitro, including troubleshooting technical issues as they arise. Strong interpersonal, verbal, and written communication skills are required. Experimental rigor, scientific curiosity, and the ability to work in a fast-paced environment, adapting to evolving priorities, are musts. The ideal candidate for this position will have a background in immuno-oncology and hands-on experience of in vitro research. This is a full-time, on-site position based in Medicon Village in Lund, Sweden.
Key responsibilities
- Perform cell based assays and molecular biology protocols including cell culture, primary sample processing, transfection, transduction, immune assays, and flow cytometry.
- Perform method development and optimization of in vitro assays and techniques.
- Perform data analysis and critical interpretation of results.
- Maintain accurate records including electronic laboratory notebooks.
- Compile study summaries and contribute to writing study reports.
- Support scientists across projects
- Prepare study materials, reagents, and test articles in accordance with study protocols.
- Maintain laboratory equipment and ensure proper organization of laboratory areas.
Qualifications
- BSc degree in Immunology, Cancer Biology, Biomedicine, Biotechnology, or related life science discipline. MSc is a plus.
- Hands-on experience with cell-based and molecular biology workflows, cell line establishment, and handling of tissue (e.g., tumor, spleen, lymph nodes) and blood samples.
- Strong hands-on experience with tumor biology-related in vitro assays, for example multi-color flow cytometry, ELISA, ELISPOT and T cell activation assays.
- Basic understanding of cancer immunotherapies. Knowledge of dendritic cell and T cell biology is a plus.
- Strong organizational skills and ability to work in a team-oriented environment.
- Good written and verbal communication skills in English.
Literature
- Ascic E, at al. In vivo dendritic cell reprogramming for cancer immunotherapy. Science 386, eadn9083 (2024). DOI:10.1126/science.adn9083
- Zimmermannova O, et al. Restoring Tumor Immunogenicity with Dendritic Cell Reprogramming. Science Immunology 8, eadd4817 (2023). DOI: 10.1126/sciimmunol.add4817
Application
Please email your CV, cover letter, and contact information for two references to careers@asgardthx.com to apply. Asgard will review applications on a rolling basis and only shortlisted candidates will be contacted.